Hewitt, Nicola : rechercher sur Z-Library

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1

Neural Interaction between Logical Reasoning and Pragmatic Processing in Narrative Discourse

Prado, Jérôme, Spotorno, Nicola, Koun, Eric, Hewitt, Emily, Van der Henst, Jean-Baptiste, Sperber, Dan, Noveck, Ira A.

Journal:

Journal of Cognitive Neuroscience

Année:

2015

Langue:

english

Fichier:

PDF, 398 KB

english, 2015

2

Reasons for adolescent deliberate self-harm: a cry of pain and/or a cry for help?

Gerrit Scoliers, Gwendolyn Portzky, Nicola Madge, Anthea Hewitt, Keith Hawton, Erik Jan de Wilde, Mette Ystgaard, Ella Arensman, Diego De Leo, Sandor Fekete, Kees van Heeringen

Journal:

Social Psychiatry and Psychiatric Epidemiology

Année:

2009

Langue:

english

Fichier:

PDF, 190 KB

english, 2009

3

Deliberate self-harm within an international community sample of young people: comparative findings from the Child & Adolescent Self-harm in Europe (CASE) Study

Nicola Madge, Anthea Hewitt, Keith Hawton, Erik Jan de Wilde, Paul Corcoran, Sandor Fekete, Kees van Heeringen, Diego De Leo, Mette Ystgaard

Journal:

Journal of Child Psychology and Psychiatry

Année:

2008

Langue:

english

Fichier:

PDF, 206 KB

english, 2008

4

International prevalidation studies of the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay: Transferability and reproducibility

Marilyn J. Aardema, Brenda C. Barnett, Zubin Khambatta, Kerstin Reisinger, Gladys Ouedraogo-Arras, Brigitte Faquet, Anne-Claire Ginestet, Greg C. Mun, Erica L. Dahl, Nicola J. Hewitt, Raffallea Corvi,

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2010

Langue:

english

Fichier:

PDF, 462 KB

english, 2010

5

The reconstructed skin micronucleus assay (RSMN) in EpiDerm™: Detailed protocol and harmonized scoring atlas

Erica L. Dahl, Rodger Curren, Brenda C. Barnett, Zubin Khambatta, Kerstin Reisinger, Gladys Ouedraogo, Brigitte Faquet, Anne-Claire Ginestet, Greg Mun, Nicola J. Hewitt, Greg Carr, Stefan Pfuhler, Mar

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2011

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2011

6

Effective engagement for climate services: Methods in practice in China

Golding, Nicola, Hewitt, Chris, Zhang, Peiqun

Journal:

Climate Services

Année:

2017

Langue:

english

Fichier:

PDF, 184 KB

english, 2017

7

A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals

Luijten, Mirjam, Corvi, Raffaella, Mehta, Jyotigna, Corvaro, Marco, Delrue, Nathalie, Felter, Susan, Haas, Bodo, Hewitt, Nicola J., Hilton, Gina, Holmes, Thomas, Jacobs, Miriam N., Jacobs, Abigail, La

Journal:

Regulatory Toxicology and Pharmacology

Année:

2020

Fichier:

PDF, 1.45 MB

2020

8

Modelling heat transfer and dissolved species concentrations within PWR crud

Inam ul Haq, Nicolas Cinosi, Michael Bluck, Geoff Hewitt, Simon Walker

Journal:

Nuclear Engineering and Design

Année:

2011

Langue:

english

Fichier:

PDF, 906 KB

english, 2011

9

Natural killer cell cytotoxicity: how do they pull the trigger?

Nicola J. Topham, Eric W. Hewitt

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 515 KB

english, 2009

10

Prediction of hepatic clearance using cryopreserved human hepatocytes: a comparison of serum and serum-free incubations

Nadège Blanchard, Nicola J. Hewitt, Paul Silber, Hannah Jones, Philippe Coassolo, Thierry Lave

Journal:

Journal of Pharmacy and Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 198 KB

english, 2006

11

Induction of drug metabolizing enzymes: A survey of in vitro methodologies and interpretations used in the pharmaceutical industry—Do they comply with FDA recommendations?

Nicola J. Hewitt, Ruben de Kanter, Edward LeCluyse

Journal:

Chemico-Biological Interactions

Année:

2007

Langue:

english

Fichier:

PDF, 399 KB

english, 2007

12

A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: Eye irritation

Pauline McNamee, Jalila Hibatallah, Margit Costabel-Farkas, Carsten Goebel, Daisuke Araki, Eric Dufour, Nicola J. Hewitt, Penny Jones, Annette Kirst, Béatrice Le Varlet, Martin Macfarlane, Monique Mar

Journal:

Regulatory Toxicology and Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 769 KB

english, 2009

13

A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: Skin irritation

Martin Macfarlane, Penny Jones, Carsten Goebel, Eric Dufour, Joanna Rowland, Daisuke Araki, Margit Costabel-Farkas, Nicola J. Hewitt, Jalila Hibatallah, Annette Kirst, Pauline McNamee, Florian Schella

Journal:

Regulatory Toxicology and Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 311 KB

english, 2009

14

A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: Genotoxicity. A COLIPA analysis

Stefan Pfuhler, Annette Kirst, Marilyn Aardema, Norbert Banduhn, Carsten Goebel, Daisuke Araki, Margit Costabel-Farkas, Eric Dufour, Rolf Fautz, James Harvey, Nicola J. Hewitt, Jalila Hibatallah, Paul

Journal:

Regulatory Toxicology and Pharmacology

Année:

2010

Langue:

english

Fichier:

PDF, 283 KB

english, 2010

15

Corrigendum to ‘A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: Genotoxicity. A COLIPA analysis’ [Regulatory Toxicology and Pharmacology 57 (2010) 315–324]

Stefan Pfuhler, Annette Kirst, Marilyn Aardema, Norbert Banduhn, Carsten Goebel, Daisuke Araki, Margit Costabel-Farkas, Eric Dufour, Rolf Fautz, James Harvey, Nicola J. Hewitt, Jalila Hibatallah, Paul

Journal:

Regulatory Toxicology and Pharmacology

Année:

2010

Langue:

english

Fichier:

PDF, 127 KB

english, 2010

16

Differential in vitro hepatotoxicity of troglitazone and rosiglitazone among cryopreserved human hepatocytes from 37 donors

Scott Lloyd, Michael J Hayden, Yumiko Sakai, Andrew Fackett, Paul M Silber, Nicola J Hewitt, Albert P Li

Journal:

Chemico-Biological Interactions

Année:

2002

Langue:

english

Fichier:

PDF, 324 KB

english, 2002

17

Correlation between troglitazone cytotoxicity and drug metabolic enzyme activities in cryopreserved human hepatocytes

Nicola J Hewitt, Scott Lloyd, Mike Hayden, Ryan Butler, Yumiko Sakai, Ryan Springer, Andrew Fackett, Albert P Li

Journal:

Chemico-Biological Interactions

Année:

2002

Langue:

english

Fichier:

PDF, 142 KB

english, 2002

18

Xenobiotic metabolism capacities of human skin in comparison with a 3D-epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: phase II enzymes

Christine Götz, Roland Pfeiffer, Julia Tigges, Karsten Ruwiedel, Ulrike Hübenthal, Hans F Merk, Jean Krutmann, Robert J. Edwards, Josef Abel, Camilla Pease, Carsten Goebel, Nicola Hewitt, Ellen Fritsc

Journal:

Experimental Dermatology

Année:

2012

Langue:

english

Fichier:

PDF, 404 KB

english, 2012

19

Deliberate self-harm in adolescents: Comparison between those who receive help following self-harm and those who do not

Mette Ystgaard, Ella Arensman, Keith Hawton, Nicola Madge, Kees van Heeringen, Anthea Hewitt, Erik Jan de Wilde, Diego De Leo, Sandor Fekete

Journal:

Journal of Adolescence

Année:

2009

Langue:

english

Fichier:

PDF, 213 KB

english, 2009

20

The effect of EGF and the comitogen, norepinephrine, on the proliferative responses of fresh and cryopreserved rat and mouse hepatocytes

Julie A. Price, John Caldwell, Nicola J. Hewitt

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 178 KB

english, 2006

21

Evaluation of chemicals requiring metabolic activation in the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay

Marilyn J. Aardema, Brenda B. Barnett, Greg C. Mun, Erica L. Dahl, Rodger D. Curren, Nicola J. Hewitt, Stefan Pfuhler

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2013

Langue:

english

Fichier:

PDF, 574 KB

english, 2013

22

Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies

Hewitt, Nicola J., Gómez Lechón, María José, Houston, J. Brian, Hallifax, David, Brown, Hayley S., Maurel, Patrick, Kenna, J. Gerald, Gustavsson, Lena, Lohmann, Christina, Skonberg, Christian, Guillou

Journal:

Drug Metabolism Reviews

Année:

2007

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2007

23

Effects of the genotoxic compounds, benzo[a]pyrene and cyclophosphamide on phase 1 and 2 activities in EpiDerm™ models

Götz, Christine, Hewitt, Nicola J., Jermann, Erich, Tigges, Julia, Kohne, Zippora, Hübenthal, Ulrike, Krutmann, Jean, Merk, Hans F, Fritsche, Ellen

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 977 KB

english, 2012

24

New Hepatocyte In Vitro Systems for Drug Metabolism: Metabolic Capacity and Recommendations for Application in Basic Research and Drug Development, Standard Operation Procedures

Gebhardt, Rolf, Hengstler, Jan G., Müller, Dieter, Glöckner, Reinhild, Buenning, Peter, Laube, Britta, Schmelzer, Eva, Ullrich, Martina, Utesch, Dietmar, Nicola Hewitt,, Ringel, Michael, Hilz, Beate

Journal:

Drug Metabolism Reviews

Année:

2003

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2003

25

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, Patricio, Hewitt, Nicola J., Albrecht, Ute, Andersen, Melvin E., Ansari, Nariman, Bhattacharya, Sudin, Bode, Johannes Georg, Bolleyn, Jennifer, Borner, Christoph, BÃ¶ttger, Jan, Braeuning, Albe

Journal:

Archives of Toxicology

Année:

2013

Langue:

english

Fichier:

PDF, 9.16 MB

english, 2013

26

In vitro cytotoxicity and genotoxicity testing using upcyte® hepatocytes

Nörenberg, Astrid, Sonntag-Buck, Vera, Hewitt, Nicola, Heinz, Stefan, Braspenning, Joris

Journal:

Toxicology Letters

Année:

2013

Langue:

english

Fichier:

PDF, 79 KB

english, 2013

27

Optimization of upcyte® human hepatocytes for the in vitro micronucleus assay

Nörenberg, Astrid, Heinz, Stefan, Scheller, Katharina, Hewitt, Nicola J., Braspenning, Joris, Ott, Michael

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2013

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2013

28

Events of interest

Nörenberg, Astrid, Heinz, Stefan, Scheller, Katharina, Hewitt, Nicola J., Braspenning, Joris, Ott, Michael

Journal:

Journal of Vascular Surgery

Année:

1993

Langue:

english

Fichier:

PDF, 96 KB

english, 1993

29

Generation of proliferating human hepatocytes using upcyte ® technology: characterisation and applications in induction and cytotoxicity assays

Burkard, Alexandra, Dähn, Caroline, Heinz, Stefan, Zutavern, Anne, Sonntag-Buck, Vera, Maltman, Daniel, Przyborski, Stefan, Hewitt, Nicola J., Braspenning, Joris

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2012

30

A Novel Strategy for ADME Screening of Prodrugs: Combined Use of Serum and Hepatocytes to Integrate Bioactivation and Clearance, and Predict Exposure to Both Active and Prodrug to the Systemic Circulation

Hoppe, Edmund, Hewitt, Nicola J., Buchstaller, Hans-Peter, Eggenweiler, Hans-Michael, Sirrenberg, Christian, Zimmermann, Astrid, März, Joachim, Schwartz, Harry, Saal, Christoph, Meyring, Michael, Hech

Journal:

Journal of Pharmaceutical Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2014

31

Postsurgery wound assessment and management practices: a chart audit

Gillespie, Brigid M, Chaboyer, Wendy, Kang, Evelyn, Hewitt, Jayne, Nieuwenhoven, Paul, Morley, Nicola

Journal:

Journal of Clinical Nursing

Année:

2014

Langue:

english

Fichier:

PDF, 233 KB

english, 2014

32

Outbreak of Mytilopsis sallei (Récluz, 1849) (Bivalvia: Dreissenidae) in Australia

Willan, Richard C., Russell, Barry C., Murfet, Nicolas B., Moore, Kirrily L., McEnnulty, Felicity R., Horner, Suzanne K., Hewitt, Chad L., Dally, Gavin M., Campbell, Marnie L., Bourke, Sean T.

Journal:

Molluscan Research

Année:

2000

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2000

33

Cell-Cycle Protein Expression in a Population-Based Study of Ovarian and Endometrial Cancers

Felix, Ashley S., Sherman, Mark E., Hewitt, Stephen M., Gunja, Munira Z., Yang, Hannah P., Cora, Renata L., Boudreau, Vicky, Ylaya, Kris, Lissowska, Jolanta, Brinton, Louise A., Wentzensen, Nicolas

Journal:

Frontiers in Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 849 KB

english, 2015

34

Cryopreserved rat, dog and monkey hepatocytes: measurement of drug metabolizing enzymes in suspensions and cultures

Hewitt, Nicola J, Utesch, Dietmar

Journal:

Human & Experimental Toxicology

Année:

2004

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2004

35

Loss of Thy-1 inhibits alveolar development in the newborn mouse lung

Nicola, T., Hagood, J. S., James, M. L., MacEwen, M. W., Williams, T. A., Hewitt, M. M., Schwiebert, L., Bulger, A., Oparil, S., Chen, Y.-F., Ambalavanan, N.

Journal:

AJP Lung Cellular and Molecular Physiology

Année:

2009

Langue:

english

Fichier:

PDF, 3.24 MB

english, 2009

36

An Estimate of the Number of Hepatocyte Donors Required to Provide Reasonable Estimates of Human Hepatic Clearance from In Vitro Experiments

Byers, James, Bachmann, Kenneth, Eng, Heather, Katta, Anand, White, Donald, Ghosh, Ritwik, Hewitt, Nicola, Silber, Paul, Chen, Genfu

Journal:

Drug Metabolism Letters

Année:

2007

Langue:

english

Fichier:

PDF, 152 KB

english, 2007

37

Extrapolation of systemic bioavailability assessing skin absorption and epidermal and hepatic metabolism of aromatic amine hair dyes in vitro

Manwaring, John, Rothe, Helga, Obringer, Cindy, Foltz, David J., Baker, Timothy R., Troutman, John A., Hewitt, Nicola J., Goebel, Carsten

Journal:

Toxicology and Applied Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 480 KB

english, 2015

38

Optimizing pesticide spray coverage using a novel web and smartphone tool, SnapCard

Nansen, Christian, Ferguson, J. Connor, Moore, John, Groves, Lloyd, Emery, Rob, Garel, Nicolas, Hewitt, Andrew

Journal:

Agronomy for Sustainable Development

Année:

2015

Langue:

english

Fichier:

PDF, 921 KB

english, 2015

39

Effect-directed analysis supporting monitoring of aquatic environments — An in-depth overview

Brack, Werner, Ait-Aissa, Selim, Burgess, Robert M., Busch, Wibke, Creusot, Nicolas, Di Paolo, Carolina, Escher, Beate I., Mark Hewitt, L., Hilscherova, Klara, Hollender, Juliane, Hollert, Henner, Jon

Journal:

Science of The Total Environment

Année:

2016

Langue:

english

Fichier:

PDF, 4.59 MB

english, 2016

40

Failure and rescue of Preconditioning-induced Neuroprotection in Severe Stroke-like Insults

Tauskela, Joseph S., Aylsworth, Amy, Hewitt, Melissa, Brunette, Eric, Blondeau, Nicolas

Journal:

Neuropharmacology

Année:

2016

Langue:

english

Fichier:

PDF, 2.55 MB

english, 2016

41

Suitability of the in vitro Caco-2 assay to predict the oral absorption of aromatic amine hair dyes

Obringer, Cindy, Manwaring, John, Goebel, Carsten, Hewitt, Nicola J., Rothe, Helga

Journal:

Toxicology in Vitro

Année:

2016

Langue:

english

Fichier:

PDF, 485 KB

english, 2016

42

Applicability of second-generation upcyte ® human hepatocytes for use in CYP inhibition and induction studies

Ramachandran, Sarada D., Vivarès, Aurélie, Klieber, Sylvie, Hewitt, Nicola J., Muenst, Bernhard, Heinz, Stefan, Walles, Heike, Braspenning, Joris

Journal:

Pharmacology Research & Perspectives

Année:

2015

Langue:

english

Fichier:

PDF, 719 KB

english, 2015

43

Biological effect of LOXL1 coding variants associated with pseudoexfoliation syndrome

Sharma, Shiwani, Martin, Sarah, Sykes, Matthew J., Dave, Alpana, Hewitt, Alex W., Burdon, Kathryn P., Ronci, Maurizio, Voelcker, Nicolas H., Craig, Jamie E.

Journal:

Experimental Eye Research

Année:

2016

Langue:

english

Fichier:

PDF, 3.34 MB

english, 2016

44

The EpiDerm™ 3D Human Reconstructed Skin Micronucleus (RSMN) assay: Historical control data and proof of principle studies for mechanistic assay adaptations

Roy, Shambhu, Kulkarni, Rohan, Hewitt, Nicola J., Aardema, Marilyn J.

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2016

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2016

45

DNA damage response at telomeres contributes to lung ageing and chronic obstructive pulmonary disease

Birch, Jodie, Anderson, Rhys K., Correia-Melo, Clara, Jurk, Diana, Hewitt, Graeme, Marques, Francisco Madeira, Green, Nicola J., Moisey, Elizabeth, Birrell, Mark A., Belvisi, Maria G., Black, Fiona, T

Journal:

AJP Lung Cellular and Molecular Physiology

Année:

2015

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2015

46

Bacterial mutagenicity assays: Vehicle and positive control results from the standard Ames assay, the 6- and 24-well miniaturized plate incorporation assays and the Ames II™ assay

Pant, Kamala, Bruce, Shannon, Sly, Jamie, Klug Laforce, Michelle, Springer, Sandra, Cecil, Mark, Andrus, Edgar, Dakoulas, Emily, Wagner, Valentine O., Hewitt, Nicola J., Kulkarni, Rohan

Journal:

Environmental and Molecular Mutagenesis

Année:

2016

Langue:

english

Fichier:

PDF, 424 KB

english, 2016

47

Improving user engagement and uptake of climate services in China

Golding, Nicola, Hewitt, Chris, Zhang, Peiqun, Bett, Philip, Fang, Xiaoyi, Hu, Hengzhi, Nobert, Sebastien

Journal:

Climate Services

Année:

2017

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2017

48

Comparison of the Skin Penetration of 3 Metabolically Stable Chemicals Using Fresh and Frozen Human Skin

Jacques-Jamin, Carine, Duplan, Hélène, Rothe, Helga, Vaillant, Ophelie, Eilstein, Joan, Grégoire, Sebastien, Cubberley, Richard, Lange, Daniela, Ellison, Corie, Klaric, Martina, Hewitt, Nicola, Schepk

Journal:

Skin Pharmacology and Physiology

Année:

2017

Langue:

english

Fichier:

PDF, 449 KB

english, 2017

49

Skill and reliability of seasonal forecasts for the Chinese energy sector

Bett, Philip E., Thornton, Hazel E., Lockwood, Julia F., Scaife, Adam A., Golding, Nicola, Hewitt, Chris, Zhu, Rong, Zhang, Peiqun, Li, Chaofan

Journal:

Journal of Applied Meteorology and Climatology

Année:

2017

Langue:

english

Fichier:

PDF, 7.56 MB

english, 2017

50

In-vitro-only testing strategies for cosmetic ingredients: Utility of newly validated genotoxicity assays using human skin and fertilized hen's eggs

Desprez, Bertrand, Fautz, Rolf, Hoffmann, Sebastian, Hewitt, Nicola, Fowler, Paul, Reisinger, Kerstin, Kuehnl, Jochen, Ouédraogo, Gladys, Kenny, Julia, Pfuhler, Stefan

Journal:

Toxicology Letters

Année:

2017

Langue:

english

Fichier:

PDF, 60 KB

english, 2017